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A first-in-human study of the novel HIV-fusion inhibitor C34-PEG(4)-Chol

Long-acting injectable antiretroviral (LA-ARV) drugs with low toxicity profiles and propensity for drug-drug interactions are a goal for future ARV regimens. C34-PEG(4)-Chol is a novel cholesterol tagged LA HIV-fusion-inhibitor (FI). We assessed pre-clinical toxicology and first-in-human administrat...

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Detalles Bibliográficos
Autores principales:	Quinn, Killian, Traboni, Cinzia, Penchala, Sujan Dily, Bouliotis, Georgios, Doyle, Nicki, Libri, Vincenzo, Khoo, Saye, Ashby, Deborah, Weber, Jonathan, Nicosia, Alfredo, Cortese, Riccardo, Pessi, Antonello, Winston, Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572697/ https://www.ncbi.nlm.nih.gov/pubmed/28842581 http://dx.doi.org/10.1038/s41598-017-09230-0

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