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Regulation of HGF-induced hepatocyte proliferation by the small GTPase Arf6 through the PIP(2)-producing enzyme PIP5K1A
HGF and its receptor c-Met are critical molecules in various biological processes. Others and we have previously shown that the small GTPase Arf6 plays a pivotal role in HGF signaling in hepatocytes. However, the molecular mechanism of how Arf6 regulates HGF signaling is unclear. Here, we show that...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572707/ https://www.ncbi.nlm.nih.gov/pubmed/28842595 http://dx.doi.org/10.1038/s41598-017-09633-z |