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Light-independent phospholipid scramblase activity of bacteriorhodopsin from Halobacterium salinarum

The retinylidene protein bacteriorhodopsin (BR) is a heptahelical light-dependent proton pump found in the purple membrane of the archaeon Halobacterium salinarum. We now show that when reconstituted into large unilamellar vesicles, purified BR trimers exhibit light-independent lipid scramblase acti...

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Detalles Bibliográficos
Autores principales: Verchère, Alice, Ou, Wei-Lin, Ploier, Birgit, Morizumi, Takefumi, Goren, Michael A., Bütikofer, Peter, Ernst, Oliver P., Khelashvili, George, Menon, Anant K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572738/
https://www.ncbi.nlm.nih.gov/pubmed/28842688
http://dx.doi.org/10.1038/s41598-017-09835-5