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Evaluation of 5 Commercially Available Zika Virus Immunoassays
Because of the global spread of Zika virus, accurate and high-throughput diagnostic immunoassays are needed. We compared the sensitivity and specificity of 5 commercially available Zika virus serologic assays to the recommended protocol of Zika virus IgM-capture ELISA and plaque-reduction neutraliza...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572859/ https://www.ncbi.nlm.nih.gov/pubmed/28665268 http://dx.doi.org/10.3201/eid2309.162043 |
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author | Safronetz, David Sloan, Angela Stein, Derek R. Mendoza, Emelissa Barairo, Nicole Ranadheera, Charlene Scharikow, Leanne Holloway, Kimberly Robinson, Alyssia Traykova-Andonova, Maya Makowski, Kai Dimitrova, Kristina Giles, Elizabeth Hiebert, Joanne Mogk, Rhonda Beddome, Sharla Drebot, Michael |
author_facet | Safronetz, David Sloan, Angela Stein, Derek R. Mendoza, Emelissa Barairo, Nicole Ranadheera, Charlene Scharikow, Leanne Holloway, Kimberly Robinson, Alyssia Traykova-Andonova, Maya Makowski, Kai Dimitrova, Kristina Giles, Elizabeth Hiebert, Joanne Mogk, Rhonda Beddome, Sharla Drebot, Michael |
author_sort | Safronetz, David |
collection | PubMed |
description | Because of the global spread of Zika virus, accurate and high-throughput diagnostic immunoassays are needed. We compared the sensitivity and specificity of 5 commercially available Zika virus serologic assays to the recommended protocol of Zika virus IgM-capture ELISA and plaque-reduction neutralization tests. Most commercial immunoassays showed low sensitivity, which can be increased. |
format | Online Article Text |
id | pubmed-5572859 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-55728592017-09-02 Evaluation of 5 Commercially Available Zika Virus Immunoassays Safronetz, David Sloan, Angela Stein, Derek R. Mendoza, Emelissa Barairo, Nicole Ranadheera, Charlene Scharikow, Leanne Holloway, Kimberly Robinson, Alyssia Traykova-Andonova, Maya Makowski, Kai Dimitrova, Kristina Giles, Elizabeth Hiebert, Joanne Mogk, Rhonda Beddome, Sharla Drebot, Michael Emerg Infect Dis Dispatch Because of the global spread of Zika virus, accurate and high-throughput diagnostic immunoassays are needed. We compared the sensitivity and specificity of 5 commercially available Zika virus serologic assays to the recommended protocol of Zika virus IgM-capture ELISA and plaque-reduction neutralization tests. Most commercial immunoassays showed low sensitivity, which can be increased. Centers for Disease Control and Prevention 2017-09 /pmc/articles/PMC5572859/ /pubmed/28665268 http://dx.doi.org/10.3201/eid2309.162043 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Dispatch Safronetz, David Sloan, Angela Stein, Derek R. Mendoza, Emelissa Barairo, Nicole Ranadheera, Charlene Scharikow, Leanne Holloway, Kimberly Robinson, Alyssia Traykova-Andonova, Maya Makowski, Kai Dimitrova, Kristina Giles, Elizabeth Hiebert, Joanne Mogk, Rhonda Beddome, Sharla Drebot, Michael Evaluation of 5 Commercially Available Zika Virus Immunoassays |
title | Evaluation of 5 Commercially Available Zika Virus Immunoassays |
title_full | Evaluation of 5 Commercially Available Zika Virus Immunoassays |
title_fullStr | Evaluation of 5 Commercially Available Zika Virus Immunoassays |
title_full_unstemmed | Evaluation of 5 Commercially Available Zika Virus Immunoassays |
title_short | Evaluation of 5 Commercially Available Zika Virus Immunoassays |
title_sort | evaluation of 5 commercially available zika virus immunoassays |
topic | Dispatch |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572859/ https://www.ncbi.nlm.nih.gov/pubmed/28665268 http://dx.doi.org/10.3201/eid2309.162043 |
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