Impressive Response to Concomitant Platinum-based Chemotherapy and Yttrium-90 in a Patient with Heavily Pretreated Triple-negative Breast Cancer Widely Metastasized to the Liver

Metastatic triple-negative breast cancer (TNBC) constitutes a heterogeneous group of diseases with systemic treatment options limited to cytotoxic chemotherapy at the time being. The disease tends to affect visceral organs more frequently when compared to hormone receptor-positive breast cancer. The...

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Autores principales: Castrellon, Aurelio, Nguyen, Steven M, Bengoa, Federico, Botero, Ana, Raez, Luis E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573050/
https://www.ncbi.nlm.nih.gov/pubmed/28852599
http://dx.doi.org/10.7759/cureus.1402
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author Castrellon, Aurelio
Nguyen, Steven M
Bengoa, Federico
Botero, Ana
Raez, Luis E
author_facet Castrellon, Aurelio
Nguyen, Steven M
Bengoa, Federico
Botero, Ana
Raez, Luis E
author_sort Castrellon, Aurelio
collection PubMed
description Metastatic triple-negative breast cancer (TNBC) constitutes a heterogeneous group of diseases with systemic treatment options limited to cytotoxic chemotherapy at the time being. The disease tends to affect visceral organs more frequently when compared to hormone receptor-positive breast cancer. The prognoses of patients with heavily pretreated disease affecting the liver are very dismal. We present the response to radioembolization and systemic chemotherapy in a seriously ill patient who had undergone previous lines of chemotherapy for TNBC with extensive liver metastases.
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spelling pubmed-55730502017-08-29 Impressive Response to Concomitant Platinum-based Chemotherapy and Yttrium-90 in a Patient with Heavily Pretreated Triple-negative Breast Cancer Widely Metastasized to the Liver Castrellon, Aurelio Nguyen, Steven M Bengoa, Federico Botero, Ana Raez, Luis E Cureus Oncology Metastatic triple-negative breast cancer (TNBC) constitutes a heterogeneous group of diseases with systemic treatment options limited to cytotoxic chemotherapy at the time being. The disease tends to affect visceral organs more frequently when compared to hormone receptor-positive breast cancer. The prognoses of patients with heavily pretreated disease affecting the liver are very dismal. We present the response to radioembolization and systemic chemotherapy in a seriously ill patient who had undergone previous lines of chemotherapy for TNBC with extensive liver metastases. Cureus 2017-06-28 /pmc/articles/PMC5573050/ /pubmed/28852599 http://dx.doi.org/10.7759/cureus.1402 Text en Copyright © 2017, Castrellon et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Castrellon, Aurelio
Nguyen, Steven M
Bengoa, Federico
Botero, Ana
Raez, Luis E
Impressive Response to Concomitant Platinum-based Chemotherapy and Yttrium-90 in a Patient with Heavily Pretreated Triple-negative Breast Cancer Widely Metastasized to the Liver
title Impressive Response to Concomitant Platinum-based Chemotherapy and Yttrium-90 in a Patient with Heavily Pretreated Triple-negative Breast Cancer Widely Metastasized to the Liver
title_full Impressive Response to Concomitant Platinum-based Chemotherapy and Yttrium-90 in a Patient with Heavily Pretreated Triple-negative Breast Cancer Widely Metastasized to the Liver
title_fullStr Impressive Response to Concomitant Platinum-based Chemotherapy and Yttrium-90 in a Patient with Heavily Pretreated Triple-negative Breast Cancer Widely Metastasized to the Liver
title_full_unstemmed Impressive Response to Concomitant Platinum-based Chemotherapy and Yttrium-90 in a Patient with Heavily Pretreated Triple-negative Breast Cancer Widely Metastasized to the Liver
title_short Impressive Response to Concomitant Platinum-based Chemotherapy and Yttrium-90 in a Patient with Heavily Pretreated Triple-negative Breast Cancer Widely Metastasized to the Liver
title_sort impressive response to concomitant platinum-based chemotherapy and yttrium-90 in a patient with heavily pretreated triple-negative breast cancer widely metastasized to the liver
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573050/
https://www.ncbi.nlm.nih.gov/pubmed/28852599
http://dx.doi.org/10.7759/cureus.1402
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