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VEGF siRNA delivered by polycation liposome-encapsulated calcium phosphate nanoparticles for tumor angiogenesis inhibition in breast cancer

Angiogenesis plays an important role in tumor development and metastasis, and many cancer cells upregulate VEGF expression to promote angiogenesis. Silencing VEGF expression by RNA interference is expected to be a promising strategy to suppress the tumor growth. However, low transfection efficiency...

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Detalles Bibliográficos
Autores principales: Chen, Jinliang, Sun, Xiaoyi, Shao, Rong, Xu, Yichao, Gao, Jianqing, Liang, Wenquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573052/
https://www.ncbi.nlm.nih.gov/pubmed/28860767
http://dx.doi.org/10.2147/IJN.S142739