Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype

BACKGROUND: Hyperactive B cells and a continuous interferon (IFN)-α production by plasmacytoid dendritic cells (pDCs) play a key role in systemic lupus erythematosus (SLE). We asked whether the interaction between B cells and pDCs stimulated with RNA-containing immune complexes affects peripheral B...

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Detalles Bibliográficos
Autores principales: Berggren, Olof, Hagberg, Niklas, Alexsson, Andrei, Weber, Gert, Rönnblom, Lars, Eloranta, Maija-Leena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573130/
https://www.ncbi.nlm.nih.gov/pubmed/28846748
http://dx.doi.org/10.1371/journal.pone.0183946

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