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PBRM1 regulates proliferation and the cell cycle in renal cell carcinoma through a chemokine/chemokine receptor interaction pathway

PBRM1 is a novel tumor suppressor gene that can inhibit cancer cell proliferation and predict the outcome of renal cell carcinoma (RCC), but its biological role needs further elucidation. We examined expression of the PBRM1 gene in RCC cell lines and the effect of PBRM1 on cell proliferation and cel...

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Detalles Bibliográficos
Autores principales: Wang, HongKai, Qu, YuanYuan, Dai, Bo, Zhu, Yao, Shi, GuoHai, Zhu, YiPing, Shen, YiJun, Zhang, HaiLiang, Ye, DingWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573144/
https://www.ncbi.nlm.nih.gov/pubmed/28846693
http://dx.doi.org/10.1371/journal.pone.0180862