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Novel and ultra-rare damaging variants in neuropeptide signaling are associated with disordered eating behaviors

OBJECTIVE: Eating disorders develop through a combination of genetic vulnerability and environmental stress, however the genetic basis of this risk is unknown. METHODS: To understand the genetic basis of this risk, we performed whole exome sequencing on 93 unrelated individuals with eating disorders...

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Detalles Bibliográficos
Autores principales: Lutter, Michael, Bahl, Ethan, Hannah, Claire, Hofammann, Dabney, Acevedo, Summer, Cui, Huxing, McAdams, Carrie J., Michaelson, Jacob J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573281/
https://www.ncbi.nlm.nih.gov/pubmed/28846695
http://dx.doi.org/10.1371/journal.pone.0181556