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Insulin modulates the frequency of Ca(2+) oscillations in mouse pancreatic islets

Pancreatic islets can adapt to oscillatory glucose to produce synchronous insulin pulses. Can islets adapt to other oscillatory stimuli, specifically insulin? To answer this question, we stimulated islets with pulses of exogenous insulin and measured their Ca(2+) oscillations. We observed that suffi...

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Detalles Bibliográficos
Autores principales: Lee, Boah, Song, Taegeun, Lee, Kayoung, Kim, Jaeyoon, Berggren, Per-Olof, Ryu, Sung Ho, Jo, Junghyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573301/
https://www.ncbi.nlm.nih.gov/pubmed/28846705
http://dx.doi.org/10.1371/journal.pone.0183569