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Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway
Zrt/Irt-like proteins (ZIPs) play fundamental roles in metal metabolism/homeostasis and are broadly involved in numerous physiological and pathological processes. The lack of high-resolution structure of the ZIPs hinders understanding of the metal transport mechanism. We report two crystal structure...
Autores principales: | Zhang, Tuo, Liu, Jian, Fellner, Matthias, Zhang, Chi, Sui, Dexin, Hu, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573306/ https://www.ncbi.nlm.nih.gov/pubmed/28875161 http://dx.doi.org/10.1126/sciadv.1700344 |
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