Metabolomic Analysis Reveals Vitamin D-induced Decrease in Polyol Pathway and Subtle Modulation of Glycolysis in HEK293T Cells

We combined (1)H NMR metabolomics with functional and molecular biochemical assays to describe the metabolic changes elicited by vitamin D in HEK293T, an embryonic proliferative cell line adapted to high-glucose concentrations. Activation of the polyol pathway, was the most important consequence of...

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Detalles Bibliográficos
Autores principales: Santos, G. C., Zeidler, J. D., Pérez-Valencia, J. A., Sant’Anna-Silva, A. C. B., Da Poian, A. T., El-Bacha, T., Almeida, F. C. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573350/
https://www.ncbi.nlm.nih.gov/pubmed/28842639
http://dx.doi.org/10.1038/s41598-017-10006-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573350/
https://www.ncbi.nlm.nih.gov/pubmed/28842639
http://dx.doi.org/10.1038/s41598-017-10006-9

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