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Reactivation of HIV-1 from Latency by an Ingenol Derivative from Euphorbia Kansui

Cells harboring latent HIV-1 pose a major obstacle to eradication of the virus. The ‘shock and kill’ strategy has been broadly explored to purge the latent reservoir; however, none of the current latency-reversing agents (LRAs) can safely and effectively activate the latent virus in patients. In thi...

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Detalles Bibliográficos
Autores principales: Wang, Pengfei, Lu, Panpan, Qu, Xiying, Shen, Yinzhong, Zeng, Hanxian, Zhu, Xiaoli, Zhu, Yuqi, Li, Xian, Wu, Hao, Xu, Jianqing, Lu, Hongzhou, Ma, Zhongjun, Zhu, Huanzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573388/
https://www.ncbi.nlm.nih.gov/pubmed/28842560
http://dx.doi.org/10.1038/s41598-017-07157-0