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Adjunctive use of antibiotics in periodontal therapy
Periodontal diseases are infectious diseases with a mixed microbial aetiology and marked inflammatory response leading to destruction of underlying tissue. Periodontal therapy aims to eliminate pathogens associated with the disease and attain periodontal health. Periodontitis is generally treated by...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Istanbul University Faculty of Dentisty
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573506/ https://www.ncbi.nlm.nih.gov/pubmed/28955547 http://dx.doi.org/10.17096/jiufd.90144 |
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author | Barca, Ece Cifcibasi, Emine Cintan, Serdar |
author_facet | Barca, Ece Cifcibasi, Emine Cintan, Serdar |
author_sort | Barca, Ece |
collection | PubMed |
description | Periodontal diseases are infectious diseases with a mixed microbial aetiology and marked inflammatory response leading to destruction of underlying tissue. Periodontal therapy aims to eliminate pathogens associated with the disease and attain periodontal health. Periodontitis is generally treated by nonsurgical mechanical debridement and regular periodontal maintenance care. Periodontal surgery may be indicated for some patients to improve access to the root surface; however, mechanical debridement alone may not be helpful in all cases. In such cases, adjunctive systemic antibiotic therapy remains the treatment of choice. It can reach microorganisms at the base of the deep periodontal pockets and furcation areas via serum, and also affects organisms residing within gingival epithelium and connective tissue. This review aims to provide an update on clinical issues regarding when and how to prescribe systemic antibiotics in periodontal therapy. The points discussed are the mode of antibiotic action, susceptible periodontal pathogens, antibiotic dosage, antibiotic use in treatment of periodontal disease, and mechanism of bacterial resistance to each antibiotic. |
format | Online Article Text |
id | pubmed-5573506 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Istanbul University Faculty of Dentisty |
record_format | MEDLINE/PubMed |
spelling | pubmed-55735062017-09-27 Adjunctive use of antibiotics in periodontal therapy Barca, Ece Cifcibasi, Emine Cintan, Serdar J Istanb Univ Fac Dent Articles Periodontal diseases are infectious diseases with a mixed microbial aetiology and marked inflammatory response leading to destruction of underlying tissue. Periodontal therapy aims to eliminate pathogens associated with the disease and attain periodontal health. Periodontitis is generally treated by nonsurgical mechanical debridement and regular periodontal maintenance care. Periodontal surgery may be indicated for some patients to improve access to the root surface; however, mechanical debridement alone may not be helpful in all cases. In such cases, adjunctive systemic antibiotic therapy remains the treatment of choice. It can reach microorganisms at the base of the deep periodontal pockets and furcation areas via serum, and also affects organisms residing within gingival epithelium and connective tissue. This review aims to provide an update on clinical issues regarding when and how to prescribe systemic antibiotics in periodontal therapy. The points discussed are the mode of antibiotic action, susceptible periodontal pathogens, antibiotic dosage, antibiotic use in treatment of periodontal disease, and mechanism of bacterial resistance to each antibiotic. Istanbul University Faculty of Dentisty 2015-01-12 /pmc/articles/PMC5573506/ /pubmed/28955547 http://dx.doi.org/10.17096/jiufd.90144 Text en Copyright © 2015 Journal of Istanbul University Faculty of Dentistry This article is licensed under Creative Commons License Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license ( (https://creativecommons.org/licenses/by-nc-nd/4.0/) ). Users must give appropriate credit, provide a link to the license, and indicate if changes were made. Users may do so in any reasonable manner, but not in any way that suggests the journal endorses its use. The material cannot be used for commercial purposes. If the user remixes, transforms, or builds upon the material, he/she may not distribute the modified material. No warranties are given. The license may not give the user all of the permissions necessary for his/her intended use. For example, other rights such as publicity, privacy, or moral rights may limit how the material can be used. |
spellingShingle | Articles Barca, Ece Cifcibasi, Emine Cintan, Serdar Adjunctive use of antibiotics in periodontal therapy |
title | Adjunctive use of antibiotics in periodontal therapy |
title_full | Adjunctive use of antibiotics in periodontal therapy |
title_fullStr | Adjunctive use of antibiotics in periodontal therapy |
title_full_unstemmed | Adjunctive use of antibiotics in periodontal therapy |
title_short | Adjunctive use of antibiotics in periodontal therapy |
title_sort | adjunctive use of antibiotics in periodontal therapy |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573506/ https://www.ncbi.nlm.nih.gov/pubmed/28955547 http://dx.doi.org/10.17096/jiufd.90144 |
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