Contrasting effects of phosphatidylinositol 4,5‐bisphosphate on cloned TMEM16A and TMEM16B channels

BACKGROUND AND PURPOSE: Ca(2+)‐activated Cl(−) channels (CaCCs) are gated open by a rise in intracellular Ca(2+) concentration ([Ca(2+)](i)), typically provoked by activation of G(q)‐protein coupled receptors (G(q)PCR). G(q)PCR activation initiates depletion of plasmalemmal phosphatidylinositol 4,5‐...

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Detalles Bibliográficos
Autores principales: Ta, Chau M, Acheson, Kathryn E, Rorsman, Nils J G, Jongkind, Remco C, Tammaro, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573538/
https://www.ncbi.nlm.nih.gov/pubmed/28616863
http://dx.doi.org/10.1111/bph.13913

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