Cargando…

Maternal Antiviral Immunoglobulin Accumulates in Neural Tissue of Neonates To Prevent HSV Neurological Disease

While antibody responses to neurovirulent pathogens are critical for clearance, the extent to which antibodies access the nervous system to ameliorate infection is poorly understood. In this study on herpes simplex virus 1 (HSV-1), we demonstrate that HSV-specific antibodies are present during HSV-1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Yike, Patel, Chaya D., Manivanh, Richard, North, Brian, Backes, Iara M., Posner, David A., Gilli, Francesca, Pachner, Andrew R., Nguyen, Lananh N., Leib, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573671/ https://www.ncbi.nlm.nih.gov/pubmed/28679745 http://dx.doi.org/10.1128/mBio.00678-17

Ejemplares similares

Maternally transferred mAbs protect neonatal mice from HSV-induced mortality and morbidity
por: Backes, Iara M., et al.
Publicado: (2022)

The ESCRT-Related ATPase Vps4 Is Modulated by Interferon during Herpes Simplex Virus 1 Infection
por: Cabrera, Jorge Ruben, et al.
Publicado: (2019)

Antibody effector functions are required for broad and potent protection of neonates from herpes simplex virus infection
por: Slein, Matthew D., et al.
Publicado: (2023)

Monoclonal antibody therapy of herpes simplex virus: An opportunity to decrease congenital and perinatal infections
por: Backes, Iara M., et al.
Publicado: (2022)

Optimizing Antiviral Dosing for HSV and CMV Treatment in Immunocompromised Patients
por: Huntjens, Daan W., et al.
Publicado: (2023)

The CXCL13 Index as a Predictive Biomarker for Activity in Clinically Isolated Syndrome
por: Pike, Steven C., et al.
Publicado: (2023)

Neurological findings of Lyme disease.
por: Pachner, A. R., et al.
Publicado: (1984)

High-Resolution Diffusion Tensor Spinal Cord MRI Measures as Biomarkers of Disability Progression in a Rodent Model of Progressive Multiple Sclerosis
por: Gilli, Francesca, et al.
Publicado: (2016)

SeXX Matters in Multiple Sclerosis
por: Gilli, Francesca, et al.
Publicado: (2020)

Are CSF CXCL13 concentrations solely dependent on intrathecal production? A commentary on “Chemokine CXCL13 in serum, CSF, and blood–CSF barrier function”
por: DiSano, Krista D., et al.
Publicado: (2021)

Intrathecally produced CXCL13: A predictive biomarker in multiple sclerosis
por: DiSano, Krista D, et al.
Publicado: (2020)

Memory B Cells in Multiple Sclerosis: Emerging Players in Disease Pathogenesis
por: DiSano, Krista D., et al.
Publicado: (2021)

A Systematic Review of Second-Line Treatments in Antiviral Resistant Strains of HSV-1, HSV-2, and VZV
por: Lince, Kimberly C, et al.
Publicado: (2023)

Effectiveness of Early Antiviral Therapy in Disseminated Neonatal Herpes Simplex Virus 2 (HSV-2) with Fulminant Hepatic Failure
por: Mirchandani, Divya, et al.
Publicado: (2017)

Evasion of host antiviral innate immunity by HSV-1, an update
por: Su, Chenhe, et al.
Publicado: (2016)

Plasma Membrane-Derived Liposomes Exhibit Robust Antiviral Activity against HSV-1
por: Bhattacharya, Ilina, et al.
Publicado: (2022)

IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications
por: Johnson, Karen E., et al.
Publicado: (2014)

Cascade search for HSV-1 combinatorial drugs with high antiviral efficacy and low toxicity
por: Ding, Xianting, et al.
Publicado: (2012)

Potentiated virucidal activity of pomegranate rind extract (PRE) and punicalagin against Herpes simplex virus (HSV) when co-administered with zinc (II) ions, and antiviral activity of PRE against HSV and aciclovir-resistant HSV
por: Houston, David M. J., et al.
Publicado: (2017)

Novel Cationic Meso-Arylporphyrins and Their Antiviral Activity against HSV-1
por: Zhdanova, Kseniya A., et al.
Publicado: (2021)

Superior antiviral activity of IFNβ in genital HSV-1 infection
por: Schmitz, Yasmin, et al.
Publicado: (2022)

Mechanistic Understanding of the Antiviral Properties of Pistachios and Zeaxanthin against HSV-1
por: Pennisi, Rosamaria, et al.
Publicado: (2023)

Clinical utility of a molecular signature in inflammatory demyelinating disease
por: Pachner, Andrew R., et al.
Publicado: (2018)

Divergent complement system activation in two clinically distinct murine models of multiple sclerosis
por: Linzey, Michael, et al.
Publicado: (2022)

Neonatal Genital HSV-1 After Jewish Circumcision
por: Tzvi-Behr, Shimrit, et al.
Publicado: (2015)

Correction: IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications
por: Johnson, Karen E., et al.
Publicado: (2018)

Novel mutations in antiviral multiresistant HSV‐2 genital lesion: A case report
por: Khellaf, Lucas, et al.
Publicado: (2022)

Correction: Potentiated virucidal activity of pomegranate rind extract (PRE) and punicalagin against Herpes simplex virus (HSV) when co-administered with zinc (II) ions, and antiviral activity of PRE against HSV and aciclovir-resistant HSV
por: Houston, David M. J., et al.
Publicado: (2017)

A Phospho-SIM in the Antiviral Protein PML is Required for Its Recruitment to HSV-1 Genomes
por: Smith, Miles C., et al.
Publicado: (2014)

Central Nervous System Inflammatory Aggregates in the Theiler's Virus Model of Progressive Multiple Sclerosis
por: DiSano, Krista D., et al.
Publicado: (2019)

Cultural adaptation and reliability assessment of the Hammersmith neonatal neurological examination for Brazilian newborns at risk of cerebral palsy
por: Correr, Mayara Thais, et al.
Publicado: (2023)

Spontaneous and Engineered Compensatory HSV Mutants that Counteract the Host Antiviral PKR Response
por: Shah, Amish C., et al.
Publicado: (2009)

Plasmacytoid Dendritic Cells Contribute to Systemic but Not Local Antiviral Responses to HSV Infections
por: Swiecki, Melissa, et al.
Publicado: (2013)

Lactoferrin-Functionalized Noble Metal Nanoparticles as New Antivirals for HSV-2 Infection
por: Krzyzowska, Malgorzata, et al.
Publicado: (2022)

TREM2 is down-regulated by HSV1 in microglia and involved in antiviral defense in the brain
por: Fruhwürth, Stefanie, et al.
Publicado: (2023)

1410. Neonatal Herpes Simplex Virus (HSV) Infection: Is It the Only Pathogen?
por: Dendi, Alvaro, et al.
Publicado: (2020)

MMPs and ADAMs in neurological infectious diseases and multiple sclerosis
por: Muri, Lukas, et al.
Publicado: (2019)

Worldwide circulation of HSV-2 × HSV-1 recombinant strains
por: Koelle, David M., et al.
Publicado: (2017)

Differential neuro-immune patterns in two clinically relevant murine models of multiple sclerosis
por: DiSano, Krista D., et al.
Publicado: (2019)

A Replication-Defective Herpes Simplex Virus (HSV)-2 Vaccine, HSV529, is Safe and Well-Tolerated in Adults with or without HSV Infection and Induces Significant HSV-2-Specific Antibody Responses in HSV Seronegative Individuals
por: Dropulic, Lesia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_e0bej3hfd7lhn1cbs4mdp60pi6