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A CTLA-4 Antagonizing DNA Aptamer with Antitumor Effect

The successful translation of cytotoxic T lymphocyte antigen-4 (CTLA-4) blockade has revolutionized the concept of cancer immunotherapy. Although monoclonal antibody therapeutics remain the mainstream in clinical practice, aptamers are synthetic oligonucleotides that encompass antibody-mimicking fun...

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Detalles Bibliográficos
Autores principales:	Huang, Bo-Tsang, Lai, Wei-Yun, Chang, Yi-Chung, Wang, Jen-Wei, Yeh, Shauh-Der, Lin, Emily Pei-Ying, Yang, Pan-Chyr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573796/ https://www.ncbi.nlm.nih.gov/pubmed/28918052 http://dx.doi.org/10.1016/j.omtn.2017.08.006

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