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Early Postnatal but Not Late Adult Neurogenesis Is Impaired in the Pitx3-Mutant Animal Model of Parkinson's Disease

The generation of new neurons in the adult dentate gyrus has functional implications for hippocampal formation. Reduced hippocampal neurogenesis has been described in various animal models of hippocampal dysfunction such as dementia and depression, which are both common non-motor-symptoms of Parkins...

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Detalles Bibliográficos
Autores principales: Brandt, Moritz D., Krüger-Gerlach, Diana, Hermann, Andreas, Meyer, Anne K., Kim, Kwang-Soo, Storch, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573808/
https://www.ncbi.nlm.nih.gov/pubmed/28883785
http://dx.doi.org/10.3389/fnins.2017.00471