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Biochemical characterization of variants of canine CYP1A1 using heterologous expression

Cytochrome P450 1A1 (CYP1A1) is a heme-containing mono-oxygenase involved in metabolism of environmental contaminants. Two variants of dog CYP1A1 with a single residue difference were identified and designated Sap1 and Sap2. Compared with Sap1, Sap2 had a Trp50Leu substitution. The biochemical chara...

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Detalles Bibliográficos
Autores principales:	YU, Hee Jeong, LEE, Seung Heon, LEE, Seungwoo, CHOI, Yu Jung, OH, Dayoung, NAM, Ki-Hoan, YUN, YoungMin, RYU, Doug-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Veterinary Science 2017
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573817/ https://www.ncbi.nlm.nih.gov/pubmed/28652520 http://dx.doi.org/10.1292/jvms.17-0192

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