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A Systematic Review and Pooled Analysis of Select Safety Parameters Among Normal Healthy Volunteers Taking Placebo in Phase 1 Clinical Trials

A systematic review of the Bristol‐Myers Squibb normal healthy volunteers (NHVs) database identified phase 1 trials that included NHVs administered placebo with the aim of characterizing normal inter‐ and intraindividual safety parameter variability. Twenty‐five single and multiple ascending dose st...

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Detalles Bibliográficos
Autores principales:	Young, Tina C., Srinivasan, Subasree, Vetter, Marion L., Sethuraman, Venkat, Bhagwagar, Zubin, Zwirtes, Ricardo, Narasimhan, Premkumar, Chuang, Tilda, Smyth, Brendan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573961/ https://www.ncbi.nlm.nih.gov/pubmed/28510323 http://dx.doi.org/10.1002/jcph.913

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