Apremilast, an oral phosphodiesterase 4 inhibitor, in the treatment of Japanese patients with moderate to severe plaque psoriasis: Efficacy, safety and tolerability results from a phase 2b randomized controlled trial

Apremilast, an oral, small‐molecule phosphodiesterase 4 inhibitor, works intracellularly within immune cells to regulate inflammatory mediators. This phase 2b randomized, placebo‐controlled study evaluated efficacy and safety of apremilast among Japanese patients with moderate to severe plaque psori...

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Detalles Bibliográficos
Autores principales: Ohtsuki, Mamitaro, Okubo, Yukari, Komine, Mayumi, Imafuku, Shinichi, Day, Robert M., Chen, Peng, Petric, Rosemary, Maroli, Allan, Nemoto, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573969/
https://www.ncbi.nlm.nih.gov/pubmed/28391657
http://dx.doi.org/10.1111/1346-8138.13829

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