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High‐resolution gradient‐recalled echo imaging at 9.4T using 16‐channel parallel transmit simultaneous multislice spokes excitations with slice‐by‐slice flip angle homogenization

PURPOSE: In order to fully benefit from the improved signal‐to‐noise and contrast‐to‐noise ratios at 9.4T, the challenges of [Formula: see text] inhomogeneity and the long acquisition time of high‐resolution 2D gradient‐recalled echo (GRE) imaging were addressed. THEORY AND METHODS: Flip angle homog...

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Detalles Bibliográficos
Autores principales: Tse, Desmond H. Y., Wiggins, Christopher J., Poser, Benedikt A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574011/
https://www.ncbi.nlm.nih.gov/pubmed/27774641
http://dx.doi.org/10.1002/mrm.26501
Descripción
Sumario:PURPOSE: In order to fully benefit from the improved signal‐to‐noise and contrast‐to‐noise ratios at 9.4T, the challenges of [Formula: see text] inhomogeneity and the long acquisition time of high‐resolution 2D gradient‐recalled echo (GRE) imaging were addressed. THEORY AND METHODS: Flip angle homogenized excitations were achieved by parallel transmission (pTx) of 3‐spoke pulses, designed by magnitude least‐squares optimization in a slice‐by‐slice fashion; the acquisition time reduction was achieved by simultaneous multislice (SMS) pulses. The slice‐specific spokes complex radiofrequency scaling factors were applied to sinc waveforms on a per‐channel basis and combined with the other pulses in an SMS slice group to form the final SMS‐pTX pulse. Optimal spokes locations were derived from simulations. RESULTS: Flip angle maps from presaturation TurboFLASH showed improvement of flip angle homogenization with 3‐spoke pulses over CP‐mode excitation (normalized root‐mean‐square error [NRMSE] 0.357) as well as comparable excitation homogeneity across the single‐band (NRMSE 0.119), SMS‐2 (NRMSE 0.137), and SMS‐3 (NRMSE 0.132) 3‐spoke pulses. The application of the 3‐spoke SMS‐3 pulses in a 48‐slice GRE protocol, which has an in‐plane resolution of 0.28 × 0.28 mm, resulted in a 50% reduction of scan duration (total acquisition time 6:52 min including reference scans). CONCLUSION: Time‐efficient flip angle homogenized high‐resolution GRE imaging at 9.4T was accomplished by using slice‐specific SMS‐pTx spokes excitations. Magn Reson Med 78:1050–1058, 2017. © 2016 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.