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High‐resolution gradient‐recalled echo imaging at 9.4T using 16‐channel parallel transmit simultaneous multislice spokes excitations with slice‐by‐slice flip angle homogenization

PURPOSE: In order to fully benefit from the improved signal‐to‐noise and contrast‐to‐noise ratios at 9.4T, the challenges of [Formula: see text] inhomogeneity and the long acquisition time of high‐resolution 2D gradient‐recalled echo (GRE) imaging were addressed. THEORY AND METHODS: Flip angle homog...

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Autores principales: Tse, Desmond H. Y., Wiggins, Christopher J., Poser, Benedikt A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574011/
https://www.ncbi.nlm.nih.gov/pubmed/27774641
http://dx.doi.org/10.1002/mrm.26501
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author Tse, Desmond H. Y.
Wiggins, Christopher J.
Poser, Benedikt A.
author_facet Tse, Desmond H. Y.
Wiggins, Christopher J.
Poser, Benedikt A.
author_sort Tse, Desmond H. Y.
collection PubMed
description PURPOSE: In order to fully benefit from the improved signal‐to‐noise and contrast‐to‐noise ratios at 9.4T, the challenges of [Formula: see text] inhomogeneity and the long acquisition time of high‐resolution 2D gradient‐recalled echo (GRE) imaging were addressed. THEORY AND METHODS: Flip angle homogenized excitations were achieved by parallel transmission (pTx) of 3‐spoke pulses, designed by magnitude least‐squares optimization in a slice‐by‐slice fashion; the acquisition time reduction was achieved by simultaneous multislice (SMS) pulses. The slice‐specific spokes complex radiofrequency scaling factors were applied to sinc waveforms on a per‐channel basis and combined with the other pulses in an SMS slice group to form the final SMS‐pTX pulse. Optimal spokes locations were derived from simulations. RESULTS: Flip angle maps from presaturation TurboFLASH showed improvement of flip angle homogenization with 3‐spoke pulses over CP‐mode excitation (normalized root‐mean‐square error [NRMSE] 0.357) as well as comparable excitation homogeneity across the single‐band (NRMSE 0.119), SMS‐2 (NRMSE 0.137), and SMS‐3 (NRMSE 0.132) 3‐spoke pulses. The application of the 3‐spoke SMS‐3 pulses in a 48‐slice GRE protocol, which has an in‐plane resolution of 0.28 × 0.28 mm, resulted in a 50% reduction of scan duration (total acquisition time 6:52 min including reference scans). CONCLUSION: Time‐efficient flip angle homogenized high‐resolution GRE imaging at 9.4T was accomplished by using slice‐specific SMS‐pTx spokes excitations. Magn Reson Med 78:1050–1058, 2017. © 2016 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.
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spelling pubmed-55740112017-09-15 High‐resolution gradient‐recalled echo imaging at 9.4T using 16‐channel parallel transmit simultaneous multislice spokes excitations with slice‐by‐slice flip angle homogenization Tse, Desmond H. Y. Wiggins, Christopher J. Poser, Benedikt A. Magn Reson Med Full Papers—Imaging Methodology PURPOSE: In order to fully benefit from the improved signal‐to‐noise and contrast‐to‐noise ratios at 9.4T, the challenges of [Formula: see text] inhomogeneity and the long acquisition time of high‐resolution 2D gradient‐recalled echo (GRE) imaging were addressed. THEORY AND METHODS: Flip angle homogenized excitations were achieved by parallel transmission (pTx) of 3‐spoke pulses, designed by magnitude least‐squares optimization in a slice‐by‐slice fashion; the acquisition time reduction was achieved by simultaneous multislice (SMS) pulses. The slice‐specific spokes complex radiofrequency scaling factors were applied to sinc waveforms on a per‐channel basis and combined with the other pulses in an SMS slice group to form the final SMS‐pTX pulse. Optimal spokes locations were derived from simulations. RESULTS: Flip angle maps from presaturation TurboFLASH showed improvement of flip angle homogenization with 3‐spoke pulses over CP‐mode excitation (normalized root‐mean‐square error [NRMSE] 0.357) as well as comparable excitation homogeneity across the single‐band (NRMSE 0.119), SMS‐2 (NRMSE 0.137), and SMS‐3 (NRMSE 0.132) 3‐spoke pulses. The application of the 3‐spoke SMS‐3 pulses in a 48‐slice GRE protocol, which has an in‐plane resolution of 0.28 × 0.28 mm, resulted in a 50% reduction of scan duration (total acquisition time 6:52 min including reference scans). CONCLUSION: Time‐efficient flip angle homogenized high‐resolution GRE imaging at 9.4T was accomplished by using slice‐specific SMS‐pTx spokes excitations. Magn Reson Med 78:1050–1058, 2017. © 2016 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. John Wiley and Sons Inc. 2016-10-23 2017-09 /pmc/articles/PMC5574011/ /pubmed/27774641 http://dx.doi.org/10.1002/mrm.26501 Text en © 2016 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Full Papers—Imaging Methodology
Tse, Desmond H. Y.
Wiggins, Christopher J.
Poser, Benedikt A.
High‐resolution gradient‐recalled echo imaging at 9.4T using 16‐channel parallel transmit simultaneous multislice spokes excitations with slice‐by‐slice flip angle homogenization
title High‐resolution gradient‐recalled echo imaging at 9.4T using 16‐channel parallel transmit simultaneous multislice spokes excitations with slice‐by‐slice flip angle homogenization
title_full High‐resolution gradient‐recalled echo imaging at 9.4T using 16‐channel parallel transmit simultaneous multislice spokes excitations with slice‐by‐slice flip angle homogenization
title_fullStr High‐resolution gradient‐recalled echo imaging at 9.4T using 16‐channel parallel transmit simultaneous multislice spokes excitations with slice‐by‐slice flip angle homogenization
title_full_unstemmed High‐resolution gradient‐recalled echo imaging at 9.4T using 16‐channel parallel transmit simultaneous multislice spokes excitations with slice‐by‐slice flip angle homogenization
title_short High‐resolution gradient‐recalled echo imaging at 9.4T using 16‐channel parallel transmit simultaneous multislice spokes excitations with slice‐by‐slice flip angle homogenization
title_sort high‐resolution gradient‐recalled echo imaging at 9.4t using 16‐channel parallel transmit simultaneous multislice spokes excitations with slice‐by‐slice flip angle homogenization
topic Full Papers—Imaging Methodology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574011/
https://www.ncbi.nlm.nih.gov/pubmed/27774641
http://dx.doi.org/10.1002/mrm.26501
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