Cargando…
The N-Terminal Part of the Dishevelled DEP Domain Is Required for Wnt/β-Catenin Signaling in Mammalian Cells
Dishevelled (DVL) proteins are key mediators of the Wnt/β-catenin signaling pathway. All DVL proteins contain three conserved domains: DIX, PDZ, and DEP. There is a consensus in the field that the DIX domain is critical for Wnt/β-catenin signaling, but contradictory evidence regarding the function o...
Autores principales: | Paclíková, Petra, Bernatík, Ondřej, Radaszkiewicz, Tomasz Witold, Bryja, Vítězslav |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574038/ https://www.ncbi.nlm.nih.gov/pubmed/28674183 http://dx.doi.org/10.1128/MCB.00145-17 |
Ejemplares similares
-
Activity of Smurf2 Ubiquitin Ligase Is Regulated by the Wnt Pathway Protein Dishevelled
por: Bernatik, Ondrej, et al.
Publicado: (2020) -
Primary Cilia Formation Does Not Rely on WNT/β-Catenin Signaling
por: Bernatik, Ondrej, et al.
Publicado: (2021) -
Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells
por: Radaszkiewicz, Tomasz, et al.
Publicado: (2020) -
Phosphorylation-induced changes in the PDZ domain of Dishevelled 3
por: Jurásek, Miroslav, et al.
Publicado: (2021) -
A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation
por: Bernatik, Ondrej, et al.
Publicado: (2017)