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Decreased ex vivo production of interferon-gamma is associated with severity and poor prognosis in patients with lupus

BACKGROUND: Lupus pathogenesis is closely associated with interferon gamma (IFN-γ), which plays a central role in innate and adaptive immunity. The aim of this study was to evaluate the ex vivo production of IFN-γ after stimulation of peripheral blood mononuclear cells with phytohemagglutinin (PHA)...

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Detalles Bibliográficos
Autores principales: Ahn, Sung Soo, Park, Eun Seong, Shim, Joo Sung, Ha, Sang-Jun, Kim, Beom Seok, Jung, Seung Min, Lee, Sang-Won, Park, Yong-Beom, Song, Jason Jungsik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574096/
https://www.ncbi.nlm.nih.gov/pubmed/28841837
http://dx.doi.org/10.1186/s13075-017-1404-z

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