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Parathyroid Hormone (PTH) Induces Autophagy to Protect Osteocyte Cell Survival from Dexamethasone Damage

BACKGROUND: Glucocorticoids (GC) have direct adverse effects on osteocytes, the most abundant bone cell type, and play an important role in osteonecrosis of the femoral head (ONFH). Teriparatide has been reported to be an effective treatment for ONFH. However, the underlying mechanism is unclear. MA...

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Detalles Bibliográficos
Autores principales: Zhu, Liang, Chen, Jifei, Zhang, Jing, Guo, Changan, Fan, Wenshuai, Wang, Yi-ming, Yan, Zuoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574377/
https://www.ncbi.nlm.nih.gov/pubmed/28824162
http://dx.doi.org/10.12659/MSM.903432