Proteasome Inhibitor YSY01A Abrogates Constitutive STAT3 Signaling via Down-regulation of Gp130 and JAK2 in Human A549 Lung Cancer Cells

Proteasome inhibition interfering with many cell signaling pathways has been extensively explored as a therapeutic strategy for cancers. Proteasome inhibitor YSY01A is a novel agent that has shown remarkable anti-tumor effects; however, its mechanisms of action are not fully understood. Here we repo...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Yuan, Xia, Sun, Ting, Fan, Shujie, Wang, Jun, Zhou, Quan, Guo, Wei, Ran, Fuxiang, Ge, Zemei, Yang, Huayu, Li, Runtao, Cui, Jingrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574410/
https://www.ncbi.nlm.nih.gov/pubmed/28883791
http://dx.doi.org/10.3389/fphar.2017.00476

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