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Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice
The Hedgehog (Hh) signaling pathway plays a key role in cell fate specification, proliferation, and survival during mammalian development. Cells require a small organelle, the primary cilium, to respond properly to Hh signals and the key regulators of Hh signal transduction exhibit dynamic localizat...
Autores principales: | Snouffer, Ashley, Brown, Desmond, Lee, Hankyu, Walsh, Jonathon, Lupu, Floria, Norman, Ryan, Lechtreck, Karl, Ko, Hyuk Wan, Eggenschwiler, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574612/ https://www.ncbi.nlm.nih.gov/pubmed/28817564 http://dx.doi.org/10.1371/journal.pgen.1006912 |
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