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Widespread Fosfomycin Resistance in Gram-Negative Bacteria Attributable to the Chromosomal fosA Gene

Fosfomycin is a decades-old antibiotic which is being revisited because of its perceived activity against many extensively drug-resistant Gram-negative pathogens. FosA proteins are Mn(2+) and K(+)-dependent glutathione S-transferases which confer fosfomycin resistance in Gram-negative bacteria by co...

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Detalles Bibliográficos
Autores principales:	Ito, Ryota, Mustapha, Mustapha M., Tomich, Adam D., Callaghan, Jake D., McElheny, Christi L., Mettus, Roberta T., Shanks, Robert M. Q., Sluis-Cremer, Nicolas, Doi, Yohei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574708/ https://www.ncbi.nlm.nih.gov/pubmed/28851843 http://dx.doi.org/10.1128/mBio.00749-17

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