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Asporin stably expressed in the surface layer of mandibular condylar cartilage and augmented in the deeper layer with age
Mandibular condylar cartilage (MCC) exhibits dual roles both articular cartilage and growth center. Of many growth factors, TGF-β has been implicated in the growth of articular cartilage including MCC. Recently, Asporin, decoy to TGF-β, was discovered and it blocks TGF-β signaling. Asporin is expres...
Autores principales: | Miyamoto, Yutaka, Kanzaki, Hiroyuki, Wada, Satoshi, Tsuruoka, Sari, Itohiya, Kanako, Kumagai, Kenichi, Hamada, Yoshiki, Nakamura, Yoshiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574816/ https://www.ncbi.nlm.nih.gov/pubmed/28875156 http://dx.doi.org/10.1016/j.bonr.2017.07.002 |
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