Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression

The data presented in this article are related to the research article entitled “The effects of deoxyelephantopin on the cardiac delayed rectifier potassium channel current (I(Kr)) and human ether-a-go-go-related gene (hERG) expression” (Y.F. Teah, M.A. Abduraman, A. Amanah, M.I. Adenan, S.F. Sulaim...

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Autores principales: Teah, Yi Fan, Abduraman, Muhammad Asyraf, Amanah, Azimah, Adenan, Mohd Ilham, Fariza Sulaiman, Shaida, Tan, Mei Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Pharmacology, Toxicology and Pharmaceutical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574817/
https://www.ncbi.nlm.nih.gov/pubmed/28879216
http://dx.doi.org/10.1016/j.dib.2017.08.008
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author Teah, Yi Fan
Abduraman, Muhammad Asyraf
Amanah, Azimah
Adenan, Mohd Ilham
Fariza Sulaiman, Shaida
Tan, Mei Lan
author_facet Teah, Yi Fan
Abduraman, Muhammad Asyraf
Amanah, Azimah
Adenan, Mohd Ilham
Fariza Sulaiman, Shaida
Tan, Mei Lan
author_sort Teah, Yi Fan
collection PubMed
description The data presented in this article are related to the research article entitled “The effects of deoxyelephantopin on the cardiac delayed rectifier potassium channel current (I(Kr)) and human ether-a-go-go-related gene (hERG) expression” (Y.F. Teah, M.A. Abduraman, A. Amanah, M.I. Adenan, S.F. Sulaiman, M.L. Tan) [1], which the possible hERG blocking properties of deoxyelephantopin were investigated. This article describes the construction of human embryonic kidney 293 (HEK293) cells overexpressing HERG potassium channel and verification of the presence of hERG mRNA and protein expression in this recombinant cell line.
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spelling pubmed-55748172017-09-06 Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression Teah, Yi Fan Abduraman, Muhammad Asyraf Amanah, Azimah Adenan, Mohd Ilham Fariza Sulaiman, Shaida Tan, Mei Lan Data Brief Pharmacology, Toxicology and Pharmaceutical Science The data presented in this article are related to the research article entitled “The effects of deoxyelephantopin on the cardiac delayed rectifier potassium channel current (I(Kr)) and human ether-a-go-go-related gene (hERG) expression” (Y.F. Teah, M.A. Abduraman, A. Amanah, M.I. Adenan, S.F. Sulaiman, M.L. Tan) [1], which the possible hERG blocking properties of deoxyelephantopin were investigated. This article describes the construction of human embryonic kidney 293 (HEK293) cells overexpressing HERG potassium channel and verification of the presence of hERG mRNA and protein expression in this recombinant cell line. Elsevier 2017-08-12 /pmc/articles/PMC5574817/ /pubmed/28879216 http://dx.doi.org/10.1016/j.dib.2017.08.008 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Pharmacology, Toxicology and Pharmaceutical Science
Teah, Yi Fan
Abduraman, Muhammad Asyraf
Amanah, Azimah
Adenan, Mohd Ilham
Fariza Sulaiman, Shaida
Tan, Mei Lan
Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
title Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
title_full Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
title_fullStr Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
title_full_unstemmed Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
title_short Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
title_sort data on the construction of a recombinant hek293 cell line overexpressing herg potassium channel and examining the presence of herg mrna and protein expression
topic Pharmacology, Toxicology and Pharmaceutical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574817/
https://www.ncbi.nlm.nih.gov/pubmed/28879216
http://dx.doi.org/10.1016/j.dib.2017.08.008
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