Cargando…
Synaptic Activity and Muscle Contraction Increases PDK1 and PKCβI Phosphorylation in the Presynaptic Membrane of the Neuromuscular Junction
Conventional protein kinase C βI (cPKCβI) is a conventional protein kinase C (PKC) isoform directly involved in the regulation of neurotransmitter release in the neuromuscular junction (NMJ). It is located exclusively at the nerve terminal and both synaptic activity and muscle contraction modulate i...
Autores principales: | Hurtado, Erica, Cilleros, Víctor, Just, Laia, Simó, Anna, Nadal, Laura, Tomàs, Marta, Garcia, Neus, Lanuza, Maria A., Tomàs, Josep |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574929/ https://www.ncbi.nlm.nih.gov/pubmed/28890686 http://dx.doi.org/10.3389/fnmol.2017.00270 |
Ejemplares similares
-
BDNF-TrkB Signaling Coupled to nPKCε and cPKCβI Modulate the Phosphorylation of the Exocytotic Protein Munc18-1 During Synaptic Activity at the Neuromuscular Junction
por: Simó, Anna, et al.
Publicado: (2018) -
Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI
por: Hurtado, Erica, et al.
Publicado: (2017) -
PKA and PKC Balance in Synapse Elimination during Neuromuscular Junction Development
por: Garcia, Neus, et al.
Publicado: (2021) -
Presynaptic Membrane Receptors Modulate ACh Release, Axonal Competition and Synapse Elimination during Neuromuscular Junction Development
por: Tomàs, Josep, et al.
Publicado: (2017) -
The Impact of Kinases in Amyotrophic Lateral Sclerosis at the Neuromuscular Synapse: Insights into BDNF/TrkB and PKC Signaling
por: Lanuza, Maria A., et al.
Publicado: (2019)