Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq

The RNA-chaperone Hfq catalyses the annealing of bacterial small RNAs (sRNAs) with target mRNAs to regulate gene expression in response to environmental stimuli. Hfq acts on a diverse set of sRNA-mRNA pairs using a variety of different molecular mechanisms. Here, we present an unusual crystal struct...

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Detalles Bibliográficos
Autores principales: Schulz, Eike C., Seiler, Markus, Zuliani, Cecilia, Voigt, Franka, Rybin, Vladimir, Pogenberg, Vivian, Mücke, Norbert, Wilmanns, Matthias, Gibson, Toby J., Barabas, Orsolya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575007/
https://www.ncbi.nlm.nih.gov/pubmed/28852099
http://dx.doi.org/10.1038/s41598-017-10085-8

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