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Tripolar mitosis and partitioning of the genome arrests human preimplantation development in vitro

Following in vitro fertilisation (IVF), only about half of normally fertilised human embryos develop beyond cleavage and morula stages to form a blastocyst in vitro. Although many human embryos are aneuploid and genomically imbalanced, often as a result of meiotic errors inherited in the oocyte, the...

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Detalles Bibliográficos
Autores principales:	Ottolini, Christian S., Kitchen, John, Xanthopoulou, Leoni, Gordon, Tony, Summers, Michael C., Handyside, Alan H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575028/ https://www.ncbi.nlm.nih.gov/pubmed/28851957 http://dx.doi.org/10.1038/s41598-017-09693-1

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