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Label-free optical vibrational spectroscopy to detect the metabolic state of M. tuberculosis cells at the site of disease
Tuberculosis relapse is a barrier to shorter treatment. It is thought that lipid rich cells, phenotypically resistant to antibiotics, may play a major role. Most studies investigating relapse use sputum samples although tissue bacteria may play an important role. We developed a non-destructive, labe...
Autores principales: | Baron, Vincent O., Chen, Mingzhou, Clark, Simon O., Williams, Ann, Hammond, Robert J. H., Dholakia, Kishan, Gillespie, Stephen H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575044/ https://www.ncbi.nlm.nih.gov/pubmed/28852109 http://dx.doi.org/10.1038/s41598-017-10234-z |
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