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Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults

Growing evidence supports the hypothesis that type 2 diabetes (T2D) increases the risk of developing dementia. Experimental evidence from mouse models demonstrates that the induction of T2D/insulin resistance (IR) can promote the accumulation of Alzheimer’s disease (AD) pathological features. Howeve...

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Detalles Bibliográficos
Autores principales:	Laws, Simon M., Gaskin, Scott, Woodfield, Amy, Srikanth, Velandai, Bruce, David, Fraser, Paul E., Porter, Tenielle, Newsholme, Philip, Wijesekara, Nadeeja, Burnham, Samantha, Doré, Vincent, Li, Qiao-Xin, Maruff, Paul, Masters, Colin L., Rainey-Smith, Stephanie, Rowe, Christopher C., Salvado, Olivier, Villemagne, Victor L., Martins, Ralph N., Verdile, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575049/ https://www.ncbi.nlm.nih.gov/pubmed/28852028 http://dx.doi.org/10.1038/s41598-017-09577-4

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