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Sonic Hedgehog mimetic prevents leukocyte infiltration into the CNS during acute HIV infection

Infiltration of infected leukocytes culminates in establishment of a brain niche for Human Immunodeficiency Virus (HIV) during acute phase of infection, initiating an ongoing cascade of persistent viral replication and inflammation, that causes irreversible neuronal injury and HIV associated neuroco...

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Detalles Bibliográficos
Autores principales: Singh, Vir B., Singh, Meera V., Piekna-Przybylska, Dorota, Gorantla, Santhi, Poluektova, Larisa Y., Maggirwar, Sanjay B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575104/
https://www.ncbi.nlm.nih.gov/pubmed/28852071
http://dx.doi.org/10.1038/s41598-017-10241-0