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Sonic Hedgehog mimetic prevents leukocyte infiltration into the CNS during acute HIV infection
Infiltration of infected leukocytes culminates in establishment of a brain niche for Human Immunodeficiency Virus (HIV) during acute phase of infection, initiating an ongoing cascade of persistent viral replication and inflammation, that causes irreversible neuronal injury and HIV associated neuroco...
Autores principales: | Singh, Vir B., Singh, Meera V., Piekna-Przybylska, Dorota, Gorantla, Santhi, Poluektova, Larisa Y., Maggirwar, Sanjay B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575104/ https://www.ncbi.nlm.nih.gov/pubmed/28852071 http://dx.doi.org/10.1038/s41598-017-10241-0 |
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