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Cesarean section without medical indication and risks of childhood allergic disorder, attenuated by breastfeeding
Caesarean section (CS) may increase the risk of asthma and allergic diseases in children, but previous studies could not preclude the potential confounding effect of underlying medical indications for CS. We aim to assess the association between CS itself (without indications) and risks of asthma an...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575109/ https://www.ncbi.nlm.nih.gov/pubmed/28852079 http://dx.doi.org/10.1038/s41598-017-10206-3 |
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author | Chu, Shuyuan Zhang, Yunting Jiang, Yanrui Sun, Wanqi Zhu, Qi Wang, Bin Jiang, Fan Zhang, Jun |
author_facet | Chu, Shuyuan Zhang, Yunting Jiang, Yanrui Sun, Wanqi Zhu, Qi Wang, Bin Jiang, Fan Zhang, Jun |
author_sort | Chu, Shuyuan |
collection | PubMed |
description | Caesarean section (CS) may increase the risk of asthma and allergic diseases in children, but previous studies could not preclude the potential confounding effect of underlying medical indications for CS. We aim to assess the association between CS itself (without indications) and risks of asthma and allergic rhinitis in children. The 2014 Shanghai Children’s Health, Education and Lifestyle Evaluation was a large population-based survey with cluster random probability sampling in 26 primary schools in Shanghai, China, in 2014. The mode of delivery and child history of asthma and allergic rhinitis were reported by parents. We included 12639 children in our analysis. CS without medical indication was associated with an increased risk of childhood asthma. CS without medical indication and CS for fetal complications were associated with increased risks of childhood allergic rhinitis, respectively. In children fed by exclusive breastfeeding or mixed feeding in the first four months after birth, these risks were not significant. In contrast, in children fed by exclusive formula milk, CS was highly significantly associated with childhood asthma and allergic rhinitis. In conclusion, CS without medical indication was associated with increased risks of both childhood asthma and allergic rhinitis. Breastfeeding in early infancy may attenuate these risks. |
format | Online Article Text |
id | pubmed-5575109 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-55751092017-09-01 Cesarean section without medical indication and risks of childhood allergic disorder, attenuated by breastfeeding Chu, Shuyuan Zhang, Yunting Jiang, Yanrui Sun, Wanqi Zhu, Qi Wang, Bin Jiang, Fan Zhang, Jun Sci Rep Article Caesarean section (CS) may increase the risk of asthma and allergic diseases in children, but previous studies could not preclude the potential confounding effect of underlying medical indications for CS. We aim to assess the association between CS itself (without indications) and risks of asthma and allergic rhinitis in children. The 2014 Shanghai Children’s Health, Education and Lifestyle Evaluation was a large population-based survey with cluster random probability sampling in 26 primary schools in Shanghai, China, in 2014. The mode of delivery and child history of asthma and allergic rhinitis were reported by parents. We included 12639 children in our analysis. CS without medical indication was associated with an increased risk of childhood asthma. CS without medical indication and CS for fetal complications were associated with increased risks of childhood allergic rhinitis, respectively. In children fed by exclusive breastfeeding or mixed feeding in the first four months after birth, these risks were not significant. In contrast, in children fed by exclusive formula milk, CS was highly significantly associated with childhood asthma and allergic rhinitis. In conclusion, CS without medical indication was associated with increased risks of both childhood asthma and allergic rhinitis. Breastfeeding in early infancy may attenuate these risks. Nature Publishing Group UK 2017-08-29 /pmc/articles/PMC5575109/ /pubmed/28852079 http://dx.doi.org/10.1038/s41598-017-10206-3 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Chu, Shuyuan Zhang, Yunting Jiang, Yanrui Sun, Wanqi Zhu, Qi Wang, Bin Jiang, Fan Zhang, Jun Cesarean section without medical indication and risks of childhood allergic disorder, attenuated by breastfeeding |
title | Cesarean section without medical indication and risks of childhood allergic disorder, attenuated by breastfeeding |
title_full | Cesarean section without medical indication and risks of childhood allergic disorder, attenuated by breastfeeding |
title_fullStr | Cesarean section without medical indication and risks of childhood allergic disorder, attenuated by breastfeeding |
title_full_unstemmed | Cesarean section without medical indication and risks of childhood allergic disorder, attenuated by breastfeeding |
title_short | Cesarean section without medical indication and risks of childhood allergic disorder, attenuated by breastfeeding |
title_sort | cesarean section without medical indication and risks of childhood allergic disorder, attenuated by breastfeeding |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575109/ https://www.ncbi.nlm.nih.gov/pubmed/28852079 http://dx.doi.org/10.1038/s41598-017-10206-3 |
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