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Comprehensive in situ co-detection of aneuploid circulating endothelial and tumor cells

Conventional circulating tumor cell (CTC) detection strategies rely on cell surface marker EpCAM and intracellular cytokeratins (CKs) for isolation and identification, respectively. Application of such methods is considerably limited by inherent heterogeneous and dynamic expression or absence of EpC...

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Detalles Bibliográficos
Autores principales: Lin, Peter Ping, Gires, Olivier, Wang, Daisy Dandan, Li, Linda, Wang, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575124/
https://www.ncbi.nlm.nih.gov/pubmed/28852197
http://dx.doi.org/10.1038/s41598-017-10763-7