TCA cycle rewiring fosters metabolic adaptation to oxygen restriction in skeletal muscle from rodents and humans

In mammals, hypoxic stress management is under the control of the Hypoxia Inducible Factors, whose activity depends on the stabilization of their labile α subunit. In particular, the skeletal muscle appears to be able to react to changes in substrates and O(2) delivery by tuning its metabolism. The...

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Detalles Bibliográficos
Autores principales: Capitanio, Daniele, Fania, Chiara, Torretta, Enrica, Viganò, Agnese, Moriggi, Manuela, Bravatà, Valentina, Caretti, Anna, Levett, Denny Z. H., Grocott, Michael P. W., Samaja, Michele, Cerretelli, Paolo, Gelfi, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575144/
https://www.ncbi.nlm.nih.gov/pubmed/28852047
http://dx.doi.org/10.1038/s41598-017-10097-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575144/
https://www.ncbi.nlm.nih.gov/pubmed/28852047
http://dx.doi.org/10.1038/s41598-017-10097-4

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