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Intravenous rAAV2/9 injection for murine cochlear gene delivery
Gene therapy for genetic deafness is a promising approach by which to prevent hearing loss or to restore hearing after loss has occurred. Although a variety of direct approaches to introduce viral particles into the inner ear have been described, presumed physiological barriers have heretofore precl...
Autores principales: | Shibata, Seiji B., Yoshimura, Hidekane, Ranum, Paul T., Goodwin, Alexander T., Smith, Richard J. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575199/ https://www.ncbi.nlm.nih.gov/pubmed/28852025 http://dx.doi.org/10.1038/s41598-017-09805-x |
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