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A novel function of cIAP1 as a mediator of CHIP-driven eIF4E regulation

eIF4E is an initiator protein in cap-dependent translation. Its overexpression is linked to tumorigenesis in various human cancers, suggesting that the levels of eIF4E must be under tight control in normal cells. Although several eIF4E regulatory mechanisms have been demonstrated, the intracellular...

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Detalles Bibliográficos
Autores principales:	Seo, Tae Woong, Lee, Ji Sun, Choi, Ye Na, Jeong, Dar Heum, Lee, Sun Kyung, Yoo, Soon Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575267/ https://www.ncbi.nlm.nih.gov/pubmed/28852129 http://dx.doi.org/10.1038/s41598-017-10358-2

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