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BBS4 regulates the expression and secretion of FSTL1, a protein that participates in ciliogenesis and the differentiation of 3T3-L1
Bardet-Biedl syndrome is a model ciliopathy. Although the characterization of BBS proteins has evidenced their involvement in cilia, extraciliary functions for some of these proteins are also being recognized. Importantly, understanding both cilia and cilia-independent functions of the BBS proteins...
Autores principales: | Prieto-Echagüe, Victoria, Lodh, Sukanya, Colman, Laura, Bobba, Natalia, Santos, Leonardo, Katsanis, Nicholas, Escande, Carlos, Zaghloul, Norann A., Badano, Jose L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575278/ https://www.ncbi.nlm.nih.gov/pubmed/28852127 http://dx.doi.org/10.1038/s41598-017-10330-0 |
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