VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis

Release of promoter-proximally paused RNA polymerase II (RNAPII) is a recently recognized transcriptional regulatory checkpoint. The biological roles of RNAPII pause release and the mechanisms by which extracellular signals control it are incompletely understood. Here we show that VEGF stimulates RN...

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Detalles Bibliográficos
Autores principales: Chen, Jiahuan, Fu, Yi, Day, Daniel S., Sun, Ye, Wang, Shiyan, Liang, Xiaodong, Gu, Fei, Zhang, Fang, Stevens, Sean M., Zhou, Pingzhu, Li, Kai, Zhang, Yan, Lin, Ruei-zeng, Smith, Lois E. H., Zhang, Jin, Sun, Kun, Melero-Martin, Juan M., Han, Zeguang, Park, Peter J., Zhang, Bing, Pu, William T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575285/
https://www.ncbi.nlm.nih.gov/pubmed/28851877
http://dx.doi.org/10.1038/s41467-017-00405-x

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