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Delayed APC/C activation extends the first mitosis of mouse embryos

The correct temporal regulation of mitosis underpins genomic stability because it ensures the alignment of chromosomes on the mitotic spindle that is required for their proper segregation to the two daughter cells. Crucially, sister chromatid separation must be delayed until all the chromosomes have...

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Detalles Bibliográficos
Autores principales: Ajduk, Anna, Strauss, Bernhard, Pines, Jonathon, Zernicka-Goetz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575289/
https://www.ncbi.nlm.nih.gov/pubmed/28851945
http://dx.doi.org/10.1038/s41598-017-09526-1