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IRF2BP2-deficient microglia block the anxiolytic effect of enhanced postnatal care
Enhanced postnatal care (EPC) increases resilience to adversity in adulthood. Since microglia participate in shaping neural circuits, we asked how ablation of an inflammation-suppressing factor IRF2BP2 (Interferon Regulatory Factor 2 Binding Protein 2) in microglia would affect the responses to EPC....
Autores principales: | Hari, Aswin, Cruz, Shelly A., Qin, Zhaohong, Couture, Pascal, Vilmundarson, Ragnar O., Huang, Hua, Stewart, Alexandre F. R., Chen, Hsiao-Huei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575313/ https://www.ncbi.nlm.nih.gov/pubmed/28852125 http://dx.doi.org/10.1038/s41598-017-10349-3 |
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