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A large benign phyllodes tumour of the breast: A case report and literature review

INTRODUCTION: Phyllodes tumours are uncommon fibroepithelial lesions that typically grow up to 4 cm in size but 10 cm tumours known as giant phyllodes tumours have been described. We present a case report of a 20 cm benign phyllodes tumour and a literature review. PRESENTATION OF CASE: A 54 years ol...

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Autores principales: Yan, Zhiyan, Gudi, Mihir, Lim, Swee Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575441/
https://www.ncbi.nlm.nih.gov/pubmed/28854407
http://dx.doi.org/10.1016/j.ijscr.2017.08.039
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author Yan, Zhiyan
Gudi, Mihir
Lim, Swee Ho
author_facet Yan, Zhiyan
Gudi, Mihir
Lim, Swee Ho
author_sort Yan, Zhiyan
collection PubMed
description INTRODUCTION: Phyllodes tumours are uncommon fibroepithelial lesions that typically grow up to 4 cm in size but 10 cm tumours known as giant phyllodes tumours have been described. We present a case report of a 20 cm benign phyllodes tumour and a literature review. PRESENTATION OF CASE: A 54 years old lady with an enlarging left breast mass measuring 20 cm of 6 months duration presented to our outpatient breast clinic. She also had an incidental right parotid lump. Core biopsy of the left breast mass returned as a cellular fibroepithelial lesion. A mastectomy and axillary lymph node sampling were done and skin cover was obtained from a split skin graft from the thigh. Final histology returned as a benign phyllodes tumour. Her post-operative recovery was uneventful. DISCUSSION: Phyllodes tumours are suspected in middle age women with rapidly enlarging painless breast masses. Though there are some suggestive features on ultrasound and MRI, the key to diagnosis is still histopathology. However, a pre-operative diagnosis may not always be possible as the interpretation of stromal cellularity and degree of atypia needed to differentiate cellular fibroadenoma from a phyllodes tumour is subjective. When a phyllodes tumour is suspected, adequate margins should be taken for optimal outcome. CONCLUSION: Successful management of phyllodes tumour involves obtaining a pre-operative diagnosis via a core biopsy when possible and planning for adequate margins.
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spelling pubmed-55754412017-09-06 A large benign phyllodes tumour of the breast: A case report and literature review Yan, Zhiyan Gudi, Mihir Lim, Swee Ho Int J Surg Case Rep Article INTRODUCTION: Phyllodes tumours are uncommon fibroepithelial lesions that typically grow up to 4 cm in size but 10 cm tumours known as giant phyllodes tumours have been described. We present a case report of a 20 cm benign phyllodes tumour and a literature review. PRESENTATION OF CASE: A 54 years old lady with an enlarging left breast mass measuring 20 cm of 6 months duration presented to our outpatient breast clinic. She also had an incidental right parotid lump. Core biopsy of the left breast mass returned as a cellular fibroepithelial lesion. A mastectomy and axillary lymph node sampling were done and skin cover was obtained from a split skin graft from the thigh. Final histology returned as a benign phyllodes tumour. Her post-operative recovery was uneventful. DISCUSSION: Phyllodes tumours are suspected in middle age women with rapidly enlarging painless breast masses. Though there are some suggestive features on ultrasound and MRI, the key to diagnosis is still histopathology. However, a pre-operative diagnosis may not always be possible as the interpretation of stromal cellularity and degree of atypia needed to differentiate cellular fibroadenoma from a phyllodes tumour is subjective. When a phyllodes tumour is suspected, adequate margins should be taken for optimal outcome. CONCLUSION: Successful management of phyllodes tumour involves obtaining a pre-operative diagnosis via a core biopsy when possible and planning for adequate margins. Elsevier 2017-08-23 /pmc/articles/PMC5575441/ /pubmed/28854407 http://dx.doi.org/10.1016/j.ijscr.2017.08.039 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Yan, Zhiyan
Gudi, Mihir
Lim, Swee Ho
A large benign phyllodes tumour of the breast: A case report and literature review
title A large benign phyllodes tumour of the breast: A case report and literature review
title_full A large benign phyllodes tumour of the breast: A case report and literature review
title_fullStr A large benign phyllodes tumour of the breast: A case report and literature review
title_full_unstemmed A large benign phyllodes tumour of the breast: A case report and literature review
title_short A large benign phyllodes tumour of the breast: A case report and literature review
title_sort large benign phyllodes tumour of the breast: a case report and literature review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575441/
https://www.ncbi.nlm.nih.gov/pubmed/28854407
http://dx.doi.org/10.1016/j.ijscr.2017.08.039
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