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Engineering a Promiscuous Tautomerase into a More Efficient Aldolase for Self‐Condensations of Linear Aliphatic Aldehydes

The enzyme 4‐oxalocrotonate tautomerase (4‐OT) from Pseudomonas putida mt‐2 takes part in a catabolic pathway for aromatic hydrocarbons, where it catalyzes the conversion of 2hydroxyhexa‐2,4‐dienedioate into 2‐oxohexa‐3‐enedioate. This tautomerase can also promiscuously catalyze carbon–carbon bond‐f...

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Detalles Bibliográficos
Autores principales:	Rahimi, Mehran, van der Meer, Jan‐Ytzen, Geertsema, Edzard M., Poelarends, Gerrit J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575498/ https://www.ncbi.nlm.nih.gov/pubmed/28426139 http://dx.doi.org/10.1002/cbic.201700121

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