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Multi‐criteria manufacturability indices for ranking high‐concentration monoclonal antibody formulations

The need for high‐concentration formulations for subcutaneous delivery of therapeutic monoclonal antibodies (mAbs) can present manufacturability challenges for the final ultrafiltration/diafiltration (UF/DF) step. Viscosity levels and the propensity to aggregate are key considerations for high‐conce...

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Detalles Bibliográficos
Autores principales:	Yang, Yang, Velayudhan, Ajoy, Thornhill, Nina F., Farid, Suzanne S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575515/ https://www.ncbi.nlm.nih.gov/pubmed/28464235 http://dx.doi.org/10.1002/bit.26329

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